If your doctor prescribed you that, I think you seriously need to look into finding a new doctor and getting a 2nd opinion. That sounds like a dangerous dose of Wellbutrin to take.

i've been put on Wellbutrin for a long time when my diagnosis was depression. I was on Effexor too and in me, they seemed to balance out. Maybe for a while I was on the 300 mg max dose? Not sure. I know I took 150 mg a long time. Once I got the bipolar diagnosis, I only get put on antidepressants short term if very depressed, 3-4 months maximum because longer than 6 months, and I'm usually going manic.