I'm on lithium and latuda, and my one brief hypomania since starting latuda was euphoric, not irritable or mixed. I'll have to see about mixed episodes, I hope I don't have any.

Right after I got diagnosed I started depakote, and that provided some relief but lithium ended up being better. I'm weird, usually mixed episodes don't respond to lithium but to to anticonvulsants.

Mixing a mood stabilizer and and anti-psychotic is considered an effective treatment.