Oh, that is tough, but they need to focus on the fact that there are blind people who can & do lead full, satisfying lives, maybe get into a support forum or group (surely something must exist for issues like that?) I agree with you about your niece needing to focus on the future and any financial help she might get. If not a better job, I believe there are benefits you can still get for disabled children. I think you are right that God makes everyone different for a reason. It might not make sense to us right now, but the baby could turn out to do something great or be a wonderful advocate for the blind. You never know.

I didn't know him well, but there was a blind boy nearly my age who attended my church growing up. I don't know his mental status exactly, of course, since he had to go to a school for the blind, but he was always a great person to be around, funny and also very supportive (finding the positive in every tough situation).