I am BP II and take 1500 lithium and 10 celexa. From an efficacy perspective, I think everything works well........when I take them. Sometimes, I'll take 1000 a day and skip the celexa. But I'm getting back to a normal routine. A big side effect is the lithium makes me incredibly thirsty all day. I also make sure I take it with food because it can upset my stomach. Celexa doesn't really have any side effects for me, I just don't believe I need it. But my p-doc says I should take it so I do.