Not quite the same experience as you, but thought it might be helpful anyway.

Was only on Prozac a short period (relatively speaking). Got up to 40mg and didn't like how it kinda made me feel dead inside. Plus, it broke me out in full-body hives, so I had to come off of it.

Didn't like the PDOC and ultimately didn't go back to him, so was off meds for a while. Then, at some point, decided I wanted to try them again and initially talked to my PCP as I hadn't gotten another PDOC.

Put me on Effexor XR and eventually got up to 150mg. Stayed on that for 3-6 months and got lucky, finding the PDOC I'm with now. We ended up going up to 225mg and staying there for a year or two.

At one point, had an increase in my social anxiety and wanted to try a higher dose (300mg) instead of trying other meds or taking more Klonopin. Was on that dose for 2-3 months max, didn't notice anything and decided to drop back down to 225mg again.

Probably a year or so into taking Effexor XR, talked to my PDOC and decided to try out Wellbutrin XL to help with depression (largely energy, anhedonia) as well as to see if it'd do anything for my anxiety.

Got up to 450mg XL and have stayed there since. No longer on Effexor. Not because it was a bad combo; just wasn't sure it was still working. Ended up switching to Cymbalta