I think it was 2-3 weeks for me. I did not have brain zaps, but I had horrid brain fog, and I hurt so badly head to toe. I think I had extreme fatigue too. It was quite awhile ago.

I do have fibromyalgia though, and sometimes they use low dose Cymbalta (maybe around 30 mg?) to treat it. My rheumatologist flat out avoided Cymbalta for me even before I started being prescribed it by the pdoc (though I was seeing the pdoc; the pdoc just wasn't prescribing me Cymbalta when I started with the rheumatologist). The rheumatologist didn't want to prescribe something that could mess with the psych meds. But the fibro could definitely be why I hurt all over so intensely (much worse than normal fibro flares, which already hurt a lot) going off it.

I tapered the dose going off.