Hi caringmum. I'm sorry that both of your sons are dealing with bipolar disorder. Have their doctors discussed medication changes/additions?
I don't think anyone can answer your questions "in general". I know some people do well on just a moodstabilizer like Lamictal or Lithium, while others need an additional meds like an antipsychotic. Or maybe the choice of moodstabilizer or dose isn't ideal.
I hope both your sons stabilize soon.
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