I've been on Seroquel XR for about 7 months. It has helped me a lot and I´ve gained almost no weight at all (I've always been quite thin). It brought me back to life from severe depression twice. After the first depressive episode I was feeling better than now, but I'm doing okay. At least I'm suffering less, and at times I even feel fine. I guess I'm still recovering from the second depressive episode.

The negative effects are that sometimes I'm very tired in the morning, and I'm very scared that I'm going to gain weight. The risk of weight gain causes me some stress, I hope it's only temporary.

I hope that after some time I could go back to a lower dose. For me Seroquel has worked quite well.