Hello Embodiment: I noticed this is your first post here on PC. So... welcome to PsychCentral.
There is a type of depression that is referred to as "existential depression". Perhaps you're familiar with the concept? Here are links to some articles, from PsychCentral's archives on the subject:
What is Existential Depression?
Coping with Existential Depression
Existential Despair: A Deeper Cause of Human Anxiety
15 Existential Questions that Could Improve Mental Health | NLP Discoveries
Ducking Existential Questions Linked To Mental Health Issues
I hope you find PC to be of benefit.