Seroquel has been a savior for me, but it makes a lot of people groggy. I can only take the regular release version. The timed-release version has me so groggy, all I want to do is sleep, and I can't do much else on it - read, exercise, cook, even driving is scary, I'm so sleepy.

I've not been on lithium, can't speak to that.

Klonopin can cause some drowsiness, but she is not on a big dose. Does she take it at bedtime or in the morning? If she takes it once a day, she might do best taking it at bedtime.

I'd advise her to get in to see her psychiatrist or at least call the office and have the pdoc call her back.