Welcome. I haven't had high dose Seroquel help with anxiety though it has helped with mania. I do fine on the regular release, but the timed dose had me zombified, tired all day. The anger, that could be part of mania or just the bipolar in general if you are mixed or something.

I've always needed something else for the panic attacks/anxiety/PTSD.

I'm on Buspar, Klonopin, and propranolol for the anxiety. But Klonopin is a controlled benzo, addictive. If you don't have to start on it, I wouldn't because as you can see from my signature, you often become used to the low dosage and the dose creeps up & up. I tried the extended release generic of Xanax, but it didn't work nearly as well as the Klonopin.