My best result has been with fluoxetine. My pdoc originally frowned on the SSRI. I’m back on a very low dose, but wish it could be higher. It’s enough that the worst of the deep gut anxiety is tempered, at least.

Benzos have worked, but they put me to sleep. Even the lowest dose was too sedating.

Buspar made my heart do weird things, but it is very helpful to others.

Quitting caffeine helped immensely, as well. Though that is harder to stick to than it should be.