I too am Bipolar 2 and have tried what seems like everything. I was diagnosised in April of this year. I also tried Latuda and like you I had miserable side effects. I have found Seroquel to be the most helpful and it has snapped me out of the depressive episode granted I did have to go to a higher dose to make sure it also killed the hypomania. I can honestly say I'm the most stable I've been in months. It takes a while till that combo works but when it works you notice. I know it's frustrating but hang in there.