I recommend you ask your question to your psychiatrist. He/she will know if any interactions are significant and if Wellbutrin is a possible help to you. Beware of therapists (including psychologists) giving medication recommendations or criticisms. I'm sure those that do sometimes have good ideas/intentions about such things, but they are not usually qualified to make such recommendations. I've encountered some psychologists who wish they were psychiatrists, but weren't.

I take some medications that have "interactions" with each other, but again, certain interactions are not deal breakers in terms of taking together. It sort of depends on the type of interaction.

I may have taken Wellbutrin XR with Ativan at one point. I think I may have. I know I took Wellbutrin XR with Klonopin. At the time, I also took Lithium and Geodon. I don't know if they had any interaction. I sure would hope that if they did have a negative interaction that my doctor and/or pharmacist would have said something. But then again, waiting for them to say something doesn't mean you shouldn't ask the question "Do they have an interaction I should be concerned about?"

I was unable to take Wellbutrin XR for more than a week or so. It was destabilizing for me. But many people with bipolar disorder take it with success, I believe. We're all different.