persistent symptoms are a big red flag. Try changing up your routine and see if they continue. If so, report that to your doctor and ask what he might recommend be done differently(taking new meds later in the day, before or after meals, lower does in morning, higher does at night, etc.) But if you're experiencing extreme discomfort, discontinue and consult your doctor. Heal yourself from your cold or flu and then request to try again. I hope those suggestions help