Not sure, but I hope you do. Depakote and Zyprexa were real weight gainers for me, too. Seroquel not as much. I find Seroquel XR a bit friendlier than regular Seroquel, especially at doses of 450/400 mg and below.

I have no intention of going off Seroquel XR, but I recently went from 600 to 500 mg. I feel a bit peppier, motivated, and with a smaller appetite. I'll lower my dose in my signature the next time I see my psychiatrist, if he keeps me at 500 mg. I hope.

Good luck with your final Seroquel reduction!