Yes! My pdoc uses it for very stubborn cases of depression.
On occasion, some people have a strong reaction to it and vomit. Just an FYI. My pdoc had tried it for her restless legs at night and she'd had this reaction, so could not take it.
She's had some success treating her very depressed patients though.
I have not tried it yet, simply because she is trying to get my mood stabilized with Lamictal. She has also been changing meds and dosages for the past three months. If I need it once we are done tweaking meds, I will try it.
Nice to have you posting!

Just sorry you are having a tough time.

WC