A little background for me is I have been through a ton of meds and diagnosis but, currently it somewhere between Treatment resistant depression (With GAD, SAD, PTSD, Depersonalization disorder) or bipolar 2. The confusing part is I only notice hypo-manic symptoms is when I take anti-depressants alone.

I’m on 150mg Luvox and 200mg Seroquel right now which seems to help a lot with my anxiety and a little for my depression. I still feel occasionally the ‘High’ feeling come through which is strange, as it says the Seroquel is supposed to help with bipolar.

All I can say is about having a bipolar 2 “mixed state” diagnosis is that I feel the high/euphoria but just really agitated and depressed / wanting to crawl out of my skin. No real desire to do anything. To me personally, it doesn’t compare to what I have read people with bipolar 2 would go through.

My first medication I took was Prozac and spent 4 months like that not knowing any better. All the rest of the meds did the same. I have been reading that people can be on a bipolar spectrum. Things like Cychlothima / Bipolar 3 / SSRI- Induced mania/ hypomania. So just wondering can anyone relate to having these symptoms only when given an anti-depressant?

My base mood while off medications is being in a real deep depression / constant suicidal ideation / Horrible anxiety and agitation. Besides all that I have been trying to see if I can try another mood stabilizer when I see my new doctor. I was on Lamictal by itself and it didn’t help (300mg). Can’t take Lithium unfortunately due to thyroid problems. Hoping to try Depakote and switch to a different anti-depressant that would help more with the depression.

Not sure if anyone can help me understand about if even a mood-stabilizer is the proper way to go. Let’s say I get to switch to Depakote and Prozac, if I can tolerate Depakote will it make the anti-depressant work like it would normally?

It just doesn’t make sense to me how it could take my mood that was high/euphoric/agitated on a SSRI and turn it to something that I should be feeling, compared to someone who could just tolerate an anti-depressant alone. (Can it really be that simple?)

It feels like I don’t really have much left besides upping the Seroquel (Don’t feel like I can handle much more) or just trying another mood stabilizer. Anyways, if you got this far, I appreciate any help. Thanks