Zyprexa has been FDA-approved as a maintenance monotherapy for bipolar (cf. e.g. Geodon that has been approved in conjunction with Lithium or Valproate, but not as monotherapy). In terms of making me functional, yes, Zyprexa alone works. It does double duty for me, helping, alongside BOTOX injections, in the prevention of migraines. But, I also take

Gabapentin, which improves the quality of my sleep and restores my dreams - medications in general cause me to have dreamless, robotic sleep that does not feel as restoring as normal sleep

Topamax to normalize the appetite that Zyprexa makes simply humongous and out of control and as an added benefit to further stabilize the mood

Melatonin , because while it is not sufficient as a sleep medicine for me, it is probably aiding some and is definitely harmless.