Same here, except for the ECT (which doctors aren't recommending and I'm hesitant to try). Also, I haven't tried all drugs, but gave up on them after they all did basically the same thing (nothing).

My only suggestion would be to get a referral (if possible) to another specialist. Who knows... maybe one of them will be able to help, even if hopes aren't high. The same goes for talk therapists, where there's even more variation.