I was on lamictal for years went off when I developed a wicked tremor Have to go back on it It kept me hypomanic most of the time but It worked on the depression which is why I am going back on it taking zyprexa for the mania I hope it works as well as it did in the beginning It did seem to stop working after a while but not sure I may have been getting worse or life circumstances had something to do with it I hope to be taking 300mg I will ask if I can take it 3 times a day 100mg to space it out and so I do not develop tremor again we will see No side effects besides the tremor