Quote:
Originally Posted by Blue_Bird
Anyone know if it's possible for meds to affect you differently at different times in your life? I was on Seroquel several years ago and had really horrible restless legs every night, I got back on it over a month ago and now the dose was doubled 5 days ago and I don't seem to have any problems with that. I'm definitely not complaining, it was so annoying when it did that.
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One thing that can happen is you’re on different meds with it. So there are these things called cytochromes that digest the meds and if you’ve got two drugs being digested by the same type of cytochrome it can cause both drugs to become more concentrated in the body. So effectively the dose is dependent not just on how much you’re taking but how effectively it’s being cleared by cytochromes.