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Originally Posted by Day Tripper
I take 300mgs of Seroquel and 160mgs of Geodon and it doesn't come close to knocking me out to sleep. I've had to take Benadryl once again to help me sleep. I can't up the Geodon or Seroquel either because im already getting heart palpitations when I lay down to sleep. 
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Quote:
Originally Posted by Blue_Bird
I've heard that lower doses are more sedating
I take 400mg, it definitely makes me tired and I sleep well most of the time
When I was on 200mg though it made me feel drunk
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This is true according to stahls psychopharmacology....I cant remember why but the best doses for sleep are lower. The receptor binding profile is different depending on dose, it works best for sleep around 50mg.