I agree that you don't need to do a full 6 months. You may need to wait up to 6 weeks to feel the full effects and see if any side effects go away. But you should be feeling some sort of improvement by then if it's going to help. It could be you'd need to increase the dose. In terms of which ones are easiest to come off of, I think Prozac has the longest half-life of any of the SSRIs, so it's easiest. Though if you're going from trying one SSRI to another, you can generally just switch to the new one because they act on the same receptors (at least, that's what my p-doc had me do). Effexor (an SNRI) has a really short half-life and is notoriously bad to come off of. That said, you just need to see which one works for you--you may need to try a few to see which one is right for your body/mind (I've had to try quite a few, but my body is also really sensitive to medications--not just psych ones, but cold meds, pain relievers, etc.). Hope you find one that works for you!