I read recently that it is possible to rewire one's brain if they practice gratitude. Noting 3 things you are grateful for each day for 21 straight days can have this effect. Certainly its not the silver bullet and it won't cure your depression but it is easy to do. I first made the mistake of expecting each thing to be of great magnitude but instead, once I shifted to the little things It was much easier. For example, I am grateful today for the ability to take a hot shower, have a book that interesting to read, and a steaming cup of coffee.