I think it's just the normal, regular, "what is life" questions everyone asks themselves. I think the only way out of them (only way to answer them) is to search for the answers that make sense to you personally.

A book I really liked is Mihaly Csikszentmihalyi's The Evolving Self

A quote of his (not from that book I don't think) is:

“Whether we like it or not, each of us is constrained by limits on what we can do and feel. To ignore these limits leads to denial and eventually to failure. To achieve excellence, we must first understand the reality of the everyday, with all its demands and potential frustrations.”