Thunderstar - Some antidepressants can cause urinary urgency, while others can stop the flow. I have seen the urinary urgency thing with Serzone™ (nefazodone) the most, and usually in women only. I have only seen 3 case (all women) and heard of 2 more (one man and one woman).

I believe that because Serzone blocks serotonin receptors, lessening muscle tone in the ureter. This is a rare side effect, and is even rarer in men. This is due to the differences lengths of ureters between men and women. Their's are very short (also making them more prone to bladder infections) while guys are longer, so a little less tone in the muscles of the ureter doesn't make much of a difference (unless the guy has prostate problems to begin with).

I have also heard of the urinary urgency thing with Paxil™ (paroxetine), but that is even more rare.

The older tricyclic antidepressants (TCAs) can cause urinary retention, especially those that bind fairly strongly to anticholinergic receptors (eg. Elavil - amitriptyline).

I hope that this helps - Cam

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