I've had reactions and side-effects to just about everything eventually. My body doesn't respond well to meds, even though my mind might, but I do need them. I worked out 3.5 hours total today plus walking and that helped a little but I'm back to feeling low again and don't have the power to move left in me. I know meds take time and I should be patient. I'm going to bed for the night and hoping I feel better tomorrow, but not counting on it.