I do, Key. The consensus on Multiple Sclerosis is still that it's an autoimmune disease/disorder, and I was diagnosed with that in 1998. Quite often, I experience skin and joint problems. Unfortunately, I haven't found that any prescription or OTC meds help much. I've tried Meloxicam, Aleve, etc.) Icing helps sometimes - it at least numbs the area for a while. I often have burning and itching symptoms on the skin. For the areas that make sense, I use an itch relief cream or lotion. Sometimes, but not usually, some diphenhydramine helps. The draw back with that is that it makes me very sleepy, so I only take it at bed time if at all.

Maybe related (or maybe not...) I have T2 Diabetes and Progressive Muscular Atrophy (PMA).

I would be interested in finding out what others have tried and what has or hasn't helped.