I'm only on one medication for bipolar disorder, an antipsychotic at a low dose. Sometimes I add a second one prn if my sleep is not good but I don't take that one every day.

I am chronically depressed but antidepressants don't help unless I am deeply depressed and can flip me into mania so I don't take them. All of these medications can have untoward side effects so the fewer one is on the better.