i know for me i didn't gain weight on lexapro until my med doc increased the dose up to the max... so i switched to wellbutrine... that one was ok... i was on it for a couple years and got the weight back off... i had to switch to effexor because i had a really bad reaction when the insurance switched me to the generic... i was told that effexor is pretty much weight neutral... i lost 130 lbs about 6 years ago... so when my doc said maybe a few pounds is the price you have to pay to stop the panic attacks... i told him it wasn't a price i was willing to pay... hope the effexor is the answer for both of us...lyn