Has she only now stopped being medicated? Why? And is it the reason for her acting out? Or perhaps something else entirely? Maybe something to ask her.

And since this is the worst it has been, has she ever done the things that you have mentioned before? Even while being medicated? If yes, I think thats even more reason to leave.

But if you don't just want to up and go, and if these issues are largely related to her being unmedicated. If you haven't already, you could try and urge her to take medications, seek out proffessional help, since you don't know how much you can take it anymore. Sort of like an ultimatum.

Another option is the suggestion of couples therapy. The issue with that is she's mostly causing the issues by what you've said. But still could be something to explore.

If she shuts down both options or already has i think you should leave.