It's actually easy to ignore minor ups and downs amidst the background hum of our own individual issues. Even the peaks start to normalize, and as you say, they don't start to become noticeable until you've hit a point where it's often far too late.
I'm totally intrigued by the way my brain decides to have good days and bad, paying no heed to the weather, or event in my life. Glad to know it happens to others too, in a way. One less neurosis to worry about