Zoloft really helps me too but the side effects of worse sexual performance and weight gain suck. I asked my psych to keep the Zoloft (sertraline, I take the generic) dose very low (I only take 25 mg a day and have days where I skip so I can enjoy sex more but I do get more anxious and talkative when I skip doses). I also take Wellbutrin (bupropion). I really like bupropion--it helps with my depression but at too high of a dose, I can't sleep and have more anxiety so I ask for the dose to be only 100 mg or 150 mg--it doesn't feed hypomania/anxiety at these doses. I wonder if your insurance would cover bupropion? Wellbutrin/bupropion can actually help some people lose weight so if you could lower the Zoloft then compensate by adding bupropion--you might be able to lose weight. Having a healthy weight is as important to our physical health as these drugs are for our mental health. Sorry this happened to you -- the side effects of the drugs that help our mental issues can really suck.