Hi Kaika,
Sometimes it is so hard to handle people, in fact it can be frustrating. The best approach is to realize that "hard-to-get-on-people" are likely to have personality problems that happens to trigger our own flaws in personality. Thus one might say we have a a clash of personalities.
Try to find out what these flaws are and you can do so by studying a course in psychotherapy.
My approach to personality (flaws or no flaws) is that it depends on one's self-image. Thus I see the self-image being at the core of personality. For instance, if a person has a low self-image, they are likely to be sensitive to any criticism or perceive criticism against the person. A person with a low self-esteem will react more emotionally to rejection of love, or perceived respect. They tend to overreact and by doing so trigger a weak spot in out own self-image. And so we might have a self-fulfilling prophecy: that "hang-ups attract hang-ups". People with hang-ups somehow find each other to live out their "hang-ups".
The solution is to get rid of one's hang-ups and then develop some strategies of how to handle criticisms and put-downs, without triggering anger reactions.
This is the theme of my book "Getting off the Hook" which is freely available on the internet free of charge. Please start at page 36, and read the ensuing chapters. Another shortened version is at:
Self-Help Psychotherapy Course
Start off at:
What is Transactional Analysis? (TA).
This course not only gives you an insight into the "psychology" or your opponent, but your own as well. The course includes an "Assertiveness Training Program", which is really a "Conflict Resolution Course".
Have fun doing the course.