I was on Seroquel for almost seven years. Started at a dose of 300 mg....or maybe 350 (don't exactly recall). The stuff wasn't doing anything for me except knocking me out to sleep. Two years ago I finally convinced my pdoc to drop my dose way down. I was on 75, then 50, then 25.


When I started taking Seroquel I weighed 130lbs., which was fine for me. I now weigh 250 and have high blood pressure, high (bad) cholesterol, and my blood glucose is on the higher side. Oh - and chronic pain issues due to weight gain.


So the weight gain is causing serious health problems. Two weeks ago I told my pdoc that I will not take Seroquel any more. I made that very, very clear. I have been off the stuff for 2 weeks. Fortunately, the only withdrawal I've noticed is some sleep issues. My appetite has decreased. Nevertheless, I will be very surprised if my weight drops much at all. I feel like Seroquel has been a toxin for me.

Since you've gained that amount of weight I believe you need to discuss a different med with your pdoc. I wish I would have been insistent before the health problems began.