Hello Mariehunt: I see this was your first post here on PC. So... a belated welcome to you. I noticed you haven't posted anything here since this first post. So I don't know if you're still actively with us. But, since depression is something you've been dealing with for a long time, I wanted to draw your attention to this other Psych-Central-supported website for people with unrelenting depression & anxiety. Here's a link:

Project Hope & Beyond

And then here are links to 2 articles, from Psych Central's archives, on the subject of treatment resistant depression, the first by our host Dr. John Grohol, Psy.D.:

About Treatment Resistant Depression (TRD)

What You Need to Know About Treatment-Resistant Depression

I hope you're finding PC to be of benefit.