Psychotic episodes are hard on the brain and I've heard that it causes cognitive issues. To me it's really a case of damned if you do and damned if you don't. For me I've chosen the meds cause life is overall better on then than off them. I could be hit by a car tomorrow so why worry about the nebulous possible effects of a med when my life is so much smoother on that med. the meds that did me the most harm were AD and benzos as both cause mood instability. That effect was clear and noticeable stopping them was a clear benefit. With AP the clear benefit is a much more stable day to day life. Yes there's a possibility future side effects but for now the benefit outweighs risk.