Your not alone I HATE DEPAKOTE !!!! Made me feel nothing >>>like I was nothing >>>>I started burning & cutting my arms just to feel pain Got marks all up and down them now .There are far better drugs out there then Depacrap and to top it off it ****s up you liver you need to get blood work done all the time . Talk to you doctor let him or her know how you feel . It takes awhile to find out what Meds. work for you. Ask other bipolar people what work for them and what didnt .I know this must of us hate Depacrap.