I'm generally ok with travel, even with time zone changes.

There was one time I couldn't even imagine getting on a plane and missed a family vacation because of it. I could hardly sit still for very long anywhere let alone a plane for 8 hours. I was also taking Ativan at the time and got really paranoid about traveling with it (I checked with the country's embassy and found out that Ativan was illegal there. I was taking it regularly and there was no way I was going to travel without it). So I didn't go on the vacation.

But otherwise I just adust my meds based on the time zone and I'm good.