Hi, I was on Paroxetine for 17 years for PTSD and GAD. Of those 17 years, the last 10 years I was on 40mg a day. This past June (2019) I had a trigger and the Paroxetine didn't work. My internist cross-tappered me to Zoloft starting with 50mg and cutting the Paroxetine from 40mg to 20mg the first week. Then the 2 week to 15mg of Paroxetine (while still on 50mg Zoloft). I was feeling horrible (anxiety, depersonalization, depression) and she increased the Zoloft to 75mg. The third week then was 10mg Paroxetine and 75mg Zoloft. I begged her to increase the Zoloft and she increased it to 100mg. Fourth week then the Paroxetine was 5mg and, after that last week, stop. At about the 5th day after stopping the Paroxetine it was way worse than before, my internist sent me to the hospital and I was Baker-Acted. The psychiatrist at the hospital increased the Zoloft dose from 100mg to 150mg, and put me back on Paroxetine 10mg so that I can be tapered off slower. It's been 2 weeks and 2 days since the Paroxetine was started again and I'm still on Zoloft 150mg. I was given Buspar 10mg 2x a day and .50 mg Klonopin (to take as needed). I was also given Klonopin by my internist when she started to cross-taper me. It's been a total of 8 weeks and 2 days since I started the Zoloft (50mg, 75mg, 100mg and finally 150mg in those 8 weeks) and 2 weeks since the psychiatrist put me back on the 10mg of Paroxetine. I still feel the same, this is horrible! I can't even make a phone call or go outside my house. Please help me. The only thing that went away was the depersonalization, all the rest is still ongoing. I spend my days with nausea, shaking, crying uncontrollably, unable to eat as well. 1) Could this mean that the Zoloft isn't working? 2) Are these still the effects of the Paroxetine withdrawal and the re-introduction of the Paroxetine still hasn't kicked in? 3) Could this be due to the 100mg to 150mg Zoloft dose increase?

Thank you!