I tried a very closely related drug, which I will not name here, and the results were immediate and miraculous. Depression was just gone. Completely gone. Basically, a miracle. The problem was the side effects were intolerable, especially issues with balance and memory. I was devastated. Nothing has ever worked like that for me before or since.

From what I've read and having talked to some of the people at the NIMH who did the early studies on this, my concern about the current protocol for ketamine is that the dose will not be high enough for many or most patients. Maybe as they get more data they will figure it out, because this class of compound truly can be miraculous.