Ive Post this 2 times before .DEPLIN is a new med. out which is not a med. at all but a med food = vitamin Its a pure and high dose of B vitamin ( is the way I understood it )which helps your other meds. work much much better .I take low dose of all dep. my meds. to keep the side effects low I started taking deplin 3 month ago and WOW .In last 3 years ive been working hard to find the right meds. and not juist take waht was even out to me by my doc. Deplin has made the bggest inpack ! In the past i would for get to take my meds. all the time but now I look forward to taken them. I am starting to feel happy again from time to time but better yet Im not going in to that dark deep hell of a Dep. as much.