I feel you. I have no children, because I knew early on that I was not parental material. I have a small circle of good friends. I am lucky in THAT. But, one of my closest friends is an older man that I love dearly, but he can be very challenging. He is a Vietnam vet and has AO problems. he is on a million meds which I sort and keep for him.
He could be doing much better in life if he would watch his diet and get more rest. This bothers me to no end. I hate worry. Especially about someone who won't help themselves in a lot of ways. Then there are the people in your life that aren't personally involved with you but are there anyway; the boss, the co-workers, the people in official capacities that cause you to grit your teeth, etc. Days I am not at my awful job i just want to stay in the house and be left alone. But it seems I always have to deal with someone/something.