Personally I have never had much of a reaction from skipping a dose here or there of any medication, altho some people do of course.
Thinking back you have been struggling for a while now??
Do you chart your mood daily ?? I’ll admit I stopped quite a while ago , dunno why , just forgot. I think if you can kind of step back a bit you might realize this has been coming for a while. Maybe try out a mood tracker on your phone , there are loads of them now., it’s also a good distraction.
Can you contact your Pdoc ? Call in the AM , maybe a Med tweak will pull you out of it ? Also if you have a T call S/he and maybe get in soon.
Meanwhile...... can you work on a sleep routine? Keep flinging every coping skill you have at it until something sticks.
Keep posting