Hi ladyconfused. I hope you start feeling better soon. Please don't judge a medication based on 24 hours. You might want to give it at least 2 weeks before drawing any firm conclusions about its efficacy. I think it might be possible that the Lamictal decrease is playing some part in your moods. Maybe. I hope you will keep your psychiatrist up-to-date on any major observations about your moods during this major medication adjustment. Is your next appointment a little sooner than usual?