Pookyl, I would have quoted your earlier post about your Seroquel XR increase, but I couldn't for the life of me find it. I did see it quoted in another member's post. I just wanted to say that I can totally believe a Seroquel XR increase helping with depression. I find it to be an interesting antipsychotic in that respect. Sometimes increases are what work (even for certain types of depression) and sometimes decreases. It's actually the only medication of mine whose dosage is manipulated. I appreciate it. I hope you continue to feel better!