Update: I'm so glad I stuck it out! On my 5th week of Wellbutrin and I've been feeling SO much better for about the last 2 weeks. I've still been tearful and highly sensitive, but not as much as I was for the last few months. In the last 2 days I've gone from 150mg to 300mg, and I'm already noticing even more energy and motivation, Downside so far: some nightmares, and difficulty sleeping(anxiety, repeatedly waking up) in the few hours before it's time to wake up. I'm hoping these side effects go away soon, but even if they don't, it's SOOOO much better than the soul crushing depression I was feeling all summer long. My only fear is a switch to mania. Anyone know at what point anti-depressant induced mania shows up once you've started a new antidepressant? My NP seems to think it would have happened by now, but I'm skeptical and still worried about it.