Today my psychiatrist gave me a prescription for 1,000 mg (500x 2 per day) Metformin. He heard a lot of success stories about it for relief of antipsychotic-related metabolic issues (and weight loss help) during his past psychopharmaceutical conferences. We both knew it had been used for these purposes for years, but he had been reluctant to prescribe it until now.

I have had a lot of trouble losing weight on my current dose, and unfortunately my current dose seems to be the dose I'll likely need long-term. My current mix is working great, so why change my mix?

I am overweight, but not severely. About 18 lbs above the high end of my normal BMI. However, I have had high cholesterol for years now and sometimes also high triglycerides. My blood pressure isn't bad, but has increased a bit. I haven't been pre-diabetic for 9 years.

My GP has continued to avoid prescribing a statin for my cholesterol. He just continues telling me to lose weight and exercise to lower it. He obviously doesn't take 600 mg Seroquel XR! I doubt he "gets it" and I imagine he wouldn't fully approve of the Metformin. However, if I can lose some weight and lower my cholesterol by February (when I see him next) he may not have a good argument against it.

Any experiences here with Metformin? Please share.