It's a B vitamin forerunner that helps with the synthesis of new neurotransmitters and thus the Deplin just helps the anti-D do its thing better. People taking anti-depressants often seem to be low in that needed B vitamin (which you body makes but some people's have difficulty) so this just boosts things a bit. But if you're not taking an anti-depressant, there's nothing to boost.
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"Never give a sword to a man who can't dance." ~Confucius
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